Publications Recent & Frequently Cited Publications Gatti, V., Gelbs, M.J., Guerra, R.B., Gerber, M.B. , Fritton, S.P., “Interstitial Fluid Velocity is Decreased around Cortical Bone Vascular Pores and Depends on Osteocyte Position in a Rat Model of Disuse Osteoporosis,” Biomechanics and Modeling in Mechanobiology, 20:1135-1146, 2021 Gatti, V., Ghobryal, B., Gelbs, M.J., Gerber, M.B., Doty, S.B., Cardoso, L., Fritton, S.P., “Botox-induced Muscle Paralysis Induces Alters Intracortical Porosity and Osteocyte Lacunar Density in Skeletally Mature Rats,” Journal of Orthopaedic Research, 37:1153-1163, 2019. Gatti, V., Azoulay, E.M., Fritton, S.P., “Microstructural Changes Associated with Osteoporosis Negatively Affect Loading-induced Fluid Flow Around Osteocytes in Cortical Bone,” Journal of Biomechanics, 66:127-136, 2018. Sharma, D., Larriera, A.I., Palacio-Mancheno, P.E., Gatti, V., Fritton, J.C., Bromage, T.G., Cardoso, L., Doty, S.B., Fritton, S.P., “The Effects of Estrogen Deficiency on Cortical Bone Microporosity and Mineralization,” Bone, 110:1-10, 2018. Kaya ,S., Basta-Pljakic, J., Seref-Ferlengez, Z., Majeska, R.J., Cardoso, L., Bromage, T., Zhang, Q., Flach, C.R., Mendelsohn, R., Yakar, S., Fritton, S.P., Schaffler, M.B., “Lactation-Induced Changes in the Volume of Osteocyte Lacunar-Canalicular Space Alter Mechanical Properties in Cortical Bone Tissue,” Journal of Bone and Mineral Research, 32(4):688-97, 2017. Ciani, C., Sharma, D., Doty, S.B., Fritton, S.P., “Ovariectomy Enhances Mechanical Load-Induced Solute Transport around Osteocytes in Rat Cancellous Bone,” Bone 59:229-34, 2014. Palacio-Mancheno, P.E., Larriera, A.I., Doty, S.B., Cardoso, L., Fritton, S.P., “3D Assessment of Cortical Bone Porosity and Tissue Mineral Density Using High-Resolution Micro-CT: Effects of Resolution and Threshold Method,” Journal of Bone and Mineral Research, 29(1):142-50, 2014. Benalla M., Palacio-Mancheno, P.E., Fritton S.P., Cardoso L., Cowin S.C., “Dynamic Permeability of the Lacunar-Canalicular System in Human Cortical Bone,” Biomechanics and Modeling in Mechanobiology,13(4):801-12, 2014. Cardoso L., Fritton S.P., Gailani G., Benalla M., Cowin S.C., “Advances in Assessment of Bone Porosity, Permeability and Interstitial Fluid Flow,” Journal of Biomechanics, 46(2):253-65, 2013. Sharma, D., Ciani, C., Ramirez Marin, P.A., Levy, J.D., Doty, S.B., Fritton, S.P., “Alterations in the Osteocyte Lacunar-Canalicular Microenvironment due to Estrogen Deficiency,” 51(3):488-97, 2012. Fritton, S.P. and Weinbaum, S., “Fluid and Solute Transport in Bone: Flow-Induced Mechanotransduction,” Annual Review of Fluid Mechanics, 41:347-374, 2009. Ciani, C., Doty, S.B., Fritton, S.P., “An Effective Histological Staining Process to Visualize Bone Interstitial Fluid Space Using Confocal Microscopy,” Bone, 44:1015-1017, 2009. Beno, T., Yoon, Y.-J., Cowin, S.C., Fritton, S.P., “Estimation of Bone Permeability Using Accurate Microstructural Measurements,” Journal of Biomechanics, 39(13):2378-87, 2006. Ciani, C., Doty, S.B., Fritton, S.P., “Mapping Bone Interstitial Fluid Movement: Displacement of Ferritin Tracer During Histological Processing,” Bone, 37(3):379-87, 2005. Mi, L.Y., Fritton, S.P., Basu, M., Cowin, S.C., “Analysis of Avian Bone Response to Mechanical Loading, Part One: Distribution of Bone Fluid Shear Stress Induced by Bending and Axial Loading,” Biomechanics and Modeling in Mechanobiology, 4(2-3):118-131, 2005. Mi, L.Y., Basu, M., Fritton, S.P., Cowin, S.C., “Analysis of Avian Bone Response to Mechanical Loading, Part Two: Development of a Computational Connected Cellular Network to Study Bone Intercellular Communication,” Biomechanics and Modeling in Mechanobiology, 4(2-3):132-146, 2005. Wang, L., Ciani, C., Doty, S.B., Fritton, S.P., “Delineating Bone’s Interstitial Fluid Pathway In Vivo,” Bone, 34(3):499-509, 2004. Wang, L., Fritton, S.P., Weinbaum, S., Cowin, S.C., “On Bone Adaptation due to Venous Stasis,” Journal of Biomechanics, 36(10):1439-1451, 2003. Fritton, S.P. and Rubin, C.T., “In Vivo Measurement of Bone Deformations Using Strain Gages,” Chapter 8 in Bone Mechanics Handbook , Cowin, S.C. (Ed.), CRC Press, p. 8.1-8.41, 2001. Wang, L., Cowin, S.C., Weinbaum, S., Fritton, S.P., “Modeling Tracer Transport in an Osteon Under Cyclic Loading,” Annals of Biomedical Engineering , 28(10):1200-1209, 2000. Fritton, S.P., McLeod, K.J., Rubin, C.T., “Quantifying the Strain History of Bone: Spatial Uniformity and Self-similarity of Low Magnitude Strains,” Journal of Biomechanics , 33(3):317-325, 2000.